Author

H. C. Benet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Organism:rat· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Herschhorn· 2 shared A. C. Smith· 1 shared A. Sharma· 1 shared D. Parthasarathy· 1 shared G. Vilmen· 1 shared J. Sodroski· 1 shared K. Janowska· 1 shared K. R. Pothula· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

A. Herschhorn

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2 papers

Recent·Most cited

MicrobiologybioRxivSep 13, 2023

Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted / founder sensitivity to broadly neutralizing antibodies

D. Parthasarathy, K. R. Pothula, K.-M. A. Dam…·A. Herschhorn

This paper shows that some HIV-1 transmitted/founder Envs are incompletely closed, making them sensitive to antibodies targeting open conformations, and highlights the importance of Env conformational flexibility for bnAb neutralization.

DOI 10.1038/s41467-024-51656-4

humanstructural biology

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MicrobiologybioRxivAug 25, 2021

Conformation of HIV-1 Envelope governs rhesus CD4 usage and simian-human immunodeficiency virus replication

G. Vilmen, A. C. Smith, H. C. Benet…·A. Sharma

This paper shows that open conformation of HIV-1 Env allows efficient use of rhesus CD4 and enhances SHIV replication in rhesus macaques.

DOI 10.1128/mbio.02752-21

ratproteomics

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