Complete Protection of Nasal and Lung Airways Against SARS-CoV-2 Challenge by Antibody Plus Th1 Dominant N- and S-Specific T-Cell Responses to Subcutaneous Prime and Thermally-Stable Oral Boost Bivalent hAd5 Vaccination in an NHP Study
E. Gabitzsch, J. T. Safrit, M. Verma, A. Rice, P. Sieling, L. Zakin, A. Shin, B. Morimoto, H. Adisetiyo, R. Wong, A. Bezawada, K. Dinkins, J. Balint, V. Peykov, H. Garban, , P. Soon-Shiong
hAd5 spike + nucleocapsid SC prime/oral boost vaccine elicits humoral and T-cell responses and protects rhesus macaques from SARS-CoV-2 challenge.
bioRxiv · Dec 8, 2020 · PreprintImmunology