Author

H. Guak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2

Frequent Co-Authors

C. M. Krawczyk· 2 shared A. R. VanderArk· 1 shared A. Vander Ark· 1 shared B. Mabvakure· 1 shared C. Scullion· 1 shared E. Ma· 1 shared H. Shen· 1 shared I. Beddows· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

C. M. Krawczyk

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2 papers

Recent·Most cited

The histone lysine demethylase KDM5C fine-tunes gene expression to regulate dendritic cell heterogeneity and function

H. Guak, M. J. Weiland, A. R. VanderArk, L. Zhai, K. Lau, B. Mabvakure, M. Corrado, P. Davidson, S. Compton, L. DeCamp, C. Scullion, R. M. Jones, S. Nowinski, C. M. Krawczyk

This study shows KDM5C regulates dendritic cell (DC) heterogeneity and function by modulating epigenetic programming and subset balance, affecting immune responses to infection.

bioRxiv · May 28, 2023 · PreprintImmunology

PGC-1β maintains mitochondrial metabolism and restrains inflammatory gene expression

H. Guak, R. D. Sheldon, I. Beddows, A. Vander Ark, H. Shen, R. Jones, J. St. Pierre, E. Ma, C. M. Krawczyk

This study shows that PGC-1β promotes mitochondrial metabolism and suppresses inflammatory gene expression in dendritic cells.

bioRxiv · May 18, 2022Immunology