Author

H. Hickman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

G. Reynoso· 2 shared J. Shannon· 2 shared J. Wei· 2 shared J. Yewdell· 2 shared A. David· 1 shared A. Kalia· 1 shared A. Martin· 1 shared B. Davenport· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

G. Reynoso

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Chikungunya virus infection disrupts lymph node lymphatic endothelial cell composition and function via MARCO

C. Lucas, R. Sheridan, G. Reynoso, B. Davenport, M. McCarthy, A. Martin, J. Hesselberth, H. Hickman, B. Tamburini, T. Morrison

This study shows CHIKV infection disrupts lymph node lymphatic endothelial cell composition and function through MARCO interactions, leading to impaired antigen acquisition and increased inflammation.

JCI Insight · Jan 9, 2024Peer-reviewedImmunology

Paradox Found: Global Accounting of Lymphocyte Protein Synthesis

M. Seedhom, D. Dersh, J. Holly, M. Pavon-Eternod, J. Wei, L. Shores, A. David, J. Santos, H. Hickman, J. Yewdell

The paper measures protein synthesis rates in lymphocytes and finds that their in vivo elongation rates increase with activation, despite a high protein-to-ribosome ratio suggesting insufficient capacity for rapid division.

bioRxiv · Oct 31, 2022 · PreprintImmunology

Zika virus spreads through infection of lymph node-resident macrophages

H. Hickman, G. V. Reynoso, D. N. Gordon, A. Kalia, C. C. Aguilar, C. Malo, M. Aleshnick, K. Dowd, C. Cherry, J. Shannon, S. Vrba, S. Maciejewski, K. Asano, T. Pierson

This study shows Zika virus infects lymph node macrophages, which directly release virus into the blood without requiring migratory immune cells.

bioRxiv · Sep 20, 2022Microbiology

Influenza A Virus Negative Strand RNA is Translated for CD8+ T Cell Immunosurveillance

H. Hickman, J. Mays, J. Gibbs, I. Kosik, J. Magadan, K. Takeda, S. Das, G. Reynoso, B. Ngudiankama, J. Wei, J. Shannon, D. McManus, J. Yewdell

This study shows that influenza A virus negative strand RNA can be translated into proteins recognized by CD8+ T cells, challenging the notion that viral negative strands are non-coding.

bioRxiv · Feb 7, 2018Immunology