Structures of filaments from Pick’s disease reveal a novel tau protein fold
B. Falcon, W. Zhang, A. G. Murzin, G. Murshudov, H. J. Garringer, R. Vidal, R. A. Crowther, B. Ghetti, S. Scheres, M. Goedert
This paper determines the structure of tau filaments from Pick’s disease using cryo-EM, revealing a novel tau protein fold distinct from Alzheimer's disease filaments.
bioRxiv · Apr 16, 2018Biophysics