B. Falcon

Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer’s and Pick’s diseases

This study characterizes heparin-induced tau filaments using cryo-EM and immuno-EM, revealing structural diversity and differences from Alzheimer’s and Pick’s disease filaments.

Structures of filaments from Pick’s disease reveal a novel tau protein fold

This paper determines the structure of tau filaments from Pick’s disease using cryo-EM, revealing a novel tau protein fold distinct from Alzheimer's disease filaments.