BiophysicsbioRxiv
Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer’s and Pick’s diseases
W. Zhang, B. Falcon, A. G. Murzin…·S. H. W. Scheres
This study characterizes heparin-induced tau filaments using cryo-EM and immuno-EM, revealing structural diversity and differences from Alzheimer’s and Pick’s disease filaments.