H. S. Sperber

This study identifies CD73 as a marker of HIV latency, showing hypoxia enhances its expression and adenosine signaling promotes viral quiescence.

Thiol drugs inhibit SARS-CoV-2 infection in vitro and reduce lung injury in vivo, supporting their potential as COVID-19 treatments.

The paper develops a humanized mouse model to evaluate HIV eradication strategies by transplanting J-Lat cells and testing TNF's effect on viral reactivation.

This study develops a lentiviral vector targeting both HIV-1 provirus and host CXCR4 to reduce gene editing efficacy thresholds for an HIV-1 cure.

The paper identifies transperons in yeast, multiplexed mRNP particles formed by mRNAs from different chromosomes, and shows their dependence on H4 histones for function.

This study shows that Puumala virus uses both macropinocytosis and clathrin-mediated endocytosis for entry into mammalian cells, and inhibiting these pathways reduces infection.