BiophysicsCellPeer-reviewed
Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex
J. Chen, B. Malone, E. Llewellyn…·E. A. Campbell
The paper presents cryo-EM structures of the SARS-CoV-2 holo-RdRp complex with nsp13 helicase, revealing interactions and a new therapeutic target.