MicrobiologybioRxivPreprint
Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) is a druggable target involved in parasite survival, oviposition and stem cell proliferation.
G. Padalino, C. A. Celatka, H. Y. Rienhoff…·K. F. Hoffmann
This study investigates the anti-schistosomal activity of HsLSD1 inhibitors on S. mansoni life cycle stages and identifies compound 33 as effective against parasite survival, oviposition, and stem cell proliferation.
DOI 10.1101/2020.09.17.301184