Author

H.-J. Cho

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Assay:flow cytometry· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Anand· 1 shared A. Hachani· 1 shared A. Richardson· 1 shared A. S. Hayes· 1 shared A. Worden· 1 shared A. Xing· 1 shared B. Landerts· 1 shared B. P. Howden· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPlant Biology

A. Anand

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mefloquine-induced conformational shift in Cx36 N-terminal helix leading to channel closure mediated by lipid bilayer

H.-J. Cho, H. H. Lee

The paper presents cryo-EM structures of Cx36 gap junction channels bound to inhibitors, showing how these molecules induce conformational changes leading to channel closure.

Nature Communications · Oct 25, 2024Peer-reviewedBiochemistry

Homeostatic Dysregulation of Systemic CD8+ T Cell Compartment in Lung Cancer Patients

S.-W. Lee, J. S. Yun, Y. J. Kim, H.-O. Kim, H.-J. Cho, C.-K. Park, I.-J. Oh, J.-H. Cho

The paper shows cancer causes systemic CD8+ T cell homeostatic dysregulation, leading to uncontrolled differentiation and poor immune checkpoint inhibitor response.

bioRxiv · Dec 27, 2023 · PreprintImmunology

A high-throughput cytotoxicity screening platform reveals agr-independent mutations in bacteraemia-associated Staphylococcus aureus that promote intracellular persistence

A. Hachani, S. G. Giulieri, R. Guerillot, C. J. Walsh, M. Herisse, Y. M. Soe, S. L. Baines, D. R. Thomas, S. D. Cheung, A. S. Hayes, H.-J. Cho, H. J. Newton, S. Pidot, R. C. Massey, B. P. Howden, T. P. Stinear

The paper develops a high-throughput platform to identify S. aureus mutations that enhance intracellular persistence and reduce cytotoxicity, revealing agr-independent pathoadaptive mutations.

bioRxiv · Dec 11, 2022Microbiology

Efficient, selectable marker free gene targeting in soybean using novel Ochrobactrum haywardense-mediated delivery

S. Kumar, Z.-B. Lui, N. Sanyour-Doyel, B. Landerts, A. Worden, A. Anand, H.-J. Cho, J. Bolar, C. Harris, L. Huang, A. Xing, A. Richardson

This paper develops a selectable marker-free gene targeting system in soybean using Ochrobactrum haywardense-mediated delivery, achieving 3.4% targeted insertion and 90% mutation rate in T0 plants.

bioRxiv · Oct 28, 2021 · PreprintPlant Biology