Author

S.-W. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biophysics· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:chicken / avian· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Deshpande· 1 shared A. Diaz-Mendez· 1 shared A. H. Noormohammadi· 1 shared B.-K. Sohn· 1 shared C. A. Loncoman· 1 shared C. Commisso· 1 shared C.-K. Park· 1 shared D. W. Dawson· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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1 shared paperBiophysics

A. Deshpande

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Transcriptome Profiling and Characterization of Peritoneal Metastasis Ovarian Cancer Xenografts in Humanized Mice

S. W. Kang, J.-y. Lee, O.-J. Kang, Y.-M. Kim, E. K. Choi, S.-W. Lee

This study establishes a humanized mouse model of ovarian cancer to evaluate immune checkpoint inhibitor efficacy and identifies gene expression patterns associated with resistance.

Scientific Reports · May 24, 2024Peer-reviewedCancer Biology

Cell polarity proteins promote macropinocytosis in response to metabolic stress

G. Lambies, S.-W. Lee, K. Duong-Polk, P. Aza-Blanc, S. Maganti, D. W. Dawson, C. Commisso

This study identifies aPKC enzymes as regulators of macropinocytosis in PDAC cells under glutamine stress, showing their role in cell survival and tumor growth.

bioRxiv · Jan 16, 2024Cancer Biology

Homeostatic Dysregulation of Systemic CD8+ T Cell Compartment in Lung Cancer Patients

S.-W. Lee, J. S. Yun, Y. J. Kim, H.-O. Kim, H.-J. Cho, C.-K. Park, I.-J. Oh, J.-H. Cho

The paper shows cancer causes systemic CD8+ T cell homeostatic dysregulation, leading to uncontrolled differentiation and poor immune checkpoint inhibitor response.

bioRxiv · Dec 27, 2023 · PreprintImmunology

Serum-free medium increases the replication rate of the avian coronavirus infectious bronchitis virus in chicken embryo kidney cells

J. A. Quinteros, G. F. Browning, A. H. Noormohammadi, M. A. Stevenson, M. J. C. Coppo, C. A. Loncoman, N. Ficorilli, S.-W. Lee, A. Diaz-Mendez

This study shows that omitting fetal bovine serum from cell culture medium increases infectious bronchitis virus replication in chicken embryo kidney cells.

bioRxiv · Apr 30, 2021 · PreprintMicrobiology

The Dynamic Landscape of Transcription Initiation in Yeast Mitochondria

B.-K. Sohn, U. Basu, S.-W. Lee, H. Cho, J. Shen, A. Deshpande, S. S. Patel, H. Kim

This study investigates the conformational dynamics of yeast mitochondrial transcription initiation using single-molecule techniques, revealing dynamic transitions and backtracking behavior.

bioRxiv · Dec 16, 2019Biophysics