Hong Wang

Multi-Criteria Evaluation of Hibiscus mutabilis Cultivars for Food Development Using Delphi and Analytic Hierarchy Process

This study evaluates 11 Hibiscus mutabilis cultivars for food use using Delphi and AHP, identifying three top cultivars for food development.

Repetitive transcranial magnetic stimulation targeting motor cortical region induces cell-type-specific transcriptional reprogramming and behavioral recovery in non-human primate model of Rett syndrome

This study shows that rTMS targeting the motor cortex in a non-human primate model of Rett syndrome improves behavioral outcomes and induces cell-type-specific transcriptional changes.

A second-generation ''hypoxia in a pill'' rescues neurodegenerative phenotypes across distinct mouse models

This paper shows that a second-generation hypoxia-in-a-pill treatment rescues neurodegenerative phenotypes in multiple mouse models.

Capsid-specialized protein language models reveal higher-order viral architecture from sequence

This paper introduces ESMCapsid, a protein language model that detects viral capsids and infers their architecture from sequences, revealing hidden structural patterns in metagenomic data.

TEDDY: An integrative workflow for TE-chimeric isoform reconstruction and systematic characterization of TE-dependent transcriptional regulation

TEDDY reconstructs and characterizes TE-dependent isoforms across biological contexts, revealing regulatory networks and identifying novel regulators like Arid3a with clinical relevance in cancer.

Inhibition of KDEL receptors remodels the tumor microenvironment for robust T cell independent tumor regression

The paper shows that inhibiting KDELR2 in tumor cells promotes tumor regression through innate immune activation, independent of T cells, and primes anti-tumor T cells for future challenges.

Disrupted callosal connectivity underlies long-lasting sensory-motor deficits in an NMDA receptor antibody encephalitis mouse model

This study shows that exposure to anti-GluN1 mAb during development causes long-term sensory-motor deficits and callosal axon changes in mice.

ADNP Modulates SINE B2-Derived CTCF-Binding Sites during Blastocyst Formation in Mouse

The paper investigates CTCF chromatin occupancy during mouse pre-implantation development and identifies ADNP's role in modulating SINE B2-derived CTCF-binding sites.

Dynamic nucleosome organization after fertilization reveals regulatory factors for mouse zygotic genome activation

The paper studies nucleosome dynamics in mouse zygotes after fertilization, identifying factors involved in zygotic genome activation.

Single cell RNA-Seq analysis identifies molecular mechanisms controlling hypothalamic patterning and differentiation.

The paper uses scRNA-Seq to analyze mouse hypothalamic development, identifying gene expression trajectories and regional subdivisions, and reveals Nkx2.1 as a negative regulator of prethalamic identity.

Genome-wide identification and transcriptomic analysis of microRNAs across various amphioxus organs using deep sequencing

This study identifies and analyzes microRNAs across eight amphioxus organs using deep sequencing, revealing their potential roles in organ-specific functions and non-organ-specific processes.

The reduced prevalence of macrolide resistance in Mycoplasma pneumoniae clinical isolates from pediatric patients in Beijing in 2016

The study reports macrolide resistance rates in Mycoplasma pneumoniae isolates from pediatric patients in Beijing, 2016, and identifies specific mutations associated with resistance.

A novel antimicrobial alternative of microbiota metabolic product deoxycholic acid controls chicken necrotic enteritis

This study shows that deoxycholic acid, a microbial metabolic product, inhibits Clostridium perfringens growth and reduces necrotic enteritis symptoms in chickens.