GenomicsbioRxivPreprint
Global lengthening of 3′ untranslated regions of mRNAs by alternative cleavage and polyadenylation in cellular senescence
Miao Han, Guoliang Lv, Hongbo Nie…·Ting Ni
This study shows that alternative polyadenylation (APA) leads to longer 3' UTRs in senescent cells, affecting gene regulation through miRNA and RBP binding sites.