Author

I. Becher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

M. Savitski· 2 shared A. Audrey· 1 shared A. Halavatyi· 1 shared A. M. Khan· 1 shared A. Mateus· 1 shared B. Neumann· 1 shared C. Tischer· 1 shared D. Bras· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

M. Savitski

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Dextromethorphan inhibits collagen transport in the endoplasmic reticulum eliciting an anti-fibrotic response in ex-vivo and in vitro models of pulmonary fibrosis

M. M. Khan, J. Zukowska, J. Jung, G. Galea, N. Tuechler, A. Halavatyi, C. Tischer, P. Haberkant, F. Stein, F. Jung, J. Landry, A. M. Khan, V. Oorschot, I. Becher, B. Neumann, , R. Pepperkok

This study shows Dextromethorphan reduces collagen deposition in fibrotic models by inhibiting collagen trafficking in the endoplasmic reticulum.

bioRxiv · Apr 19, 2023 · PreprintCell Biology

Rules for hardening influenza A virus liquid condensates

T. A. Etibor, S. Vale-Costa, S. Sridharan, D. Bras, I. Becher, V. H. Mello, F. Ferreira, M. Alenquer, M. M. Savitski, M. J. Amorim

This study demonstrates that modulating transient interactions in influenza A virus condensates is more effective for hardening than temperature or concentration changes, offering a strategy for antiviral drug design.

bioRxiv · Aug 3, 2022Cell Biology

Deep thermal proteome profiling for detection of proteoforms and drug sensitivity biomarkers

N. Kurzawa, M. Stahl, I. Leo, E. Kunold, I. Becher, A. Audrey, G. Mermelekas, W. Huber, A. Mateus, M. Savitski, R. Jafari

The paper uses thermal proteome profiling to detect proteoforms and drug sensitivity biomarkers in acute lymphoblastic leukemia cell lines.

bioRxiv · Jun 10, 2022 · PreprintBiochemistry