Cell BiologybioRxiv
The role of sigma-1 receptor in organization of endoplasmic reticulum signaling microdomains
V. Zhemkov, J. Ditlev, W.-R. Lee…·I. Bezprozvanny
This study investigates how the sigma-1 receptor (S1R) forms cholesterol-enriched microdomains in the ER and modulates signaling through changes in membrane thickness and cholesterol concentration.
DOI 10.7554/elife.65192