Author

I. Dudanova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:microscopy & imaging analysis· 2 Research Focus:protein folding & dynamics· 2

Frequent Co-Authors

I. Riera-Tur· 3 shared M. S. Hipp· 3 shared R. Fernandez-Busnadiego· 3 shared V. A. Trinkaus· 3 shared W. Baumeister· 3 shared F. U. Hartl· 2 shared P. Yuste-Checa· 2 shared Q. Guo· 2 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersCell Biology

I. Riera-Tur

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Author profile →

4 papers

Recent·Most cited

The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds

I. Saha, P. Yuste-Checa, M. da Silva Padilha, Q. Guo, R. Körner, H. Holthusen, V. A. Trinkaus, I. Dudanova, R. Fernandez-Busnadiego, W. Baumeister, D. W. Sanders, S. Gautam, M. I. Diamond, F.-U. Hartl, M. S. Hipp

This study shows that the AAA+ chaperone VCP disaggregates Tau fibrils and generates seeding-active Tau as a byproduct, suggesting a role in aggregate removal and spreading in tauopathies.

bioRxiv · Feb 18, 2022Cell Biology

The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model

P. Yuste-Checa, V. A. Trinkaus, I. Riera-Tur, R. Imamoglu, T. Schaller, H. Wang, I. Dudanova, M. S. Hipp, A. Bracher, F. U. Hartl

This study shows that Clusterin enhances Tau aggregate seeding in a cellular model by stabilizing soluble seed species and facilitating their transfer to recipient cells.

bioRxiv · Jul 16, 2021Cell Biology

In situ architecture of neuronal alpha-Synuclein inclusions

V. A. Trinkaus, I. Riera-Tur, A. Martinez-Sanchez, F. J. B. Baeuerlein, Q. Guo, T. Arzberger, W. Baumeister, I. Dudanova, M. S. Hipp, F. U. Hartl, R. Fernandez-Busnadiego

This study uses cryo-ET to show that neuronal alpha-Synuclein inclusions contain fibrils intermixed with cellular membranes and are nucleated by oligomers.

bioRxiv · Aug 7, 2020Cell Biology

Amyloid-like aggregates cause lysosomal defects in neurons via gain-of-function toxicity

I. Riera-Tur, T. Schaefer, D. Hornburg, A. Mishra, L. Fernandez-Mosquera, D. Feigenbutz, P. Auer, M. Mann, W. Baumeister, R. Klein, F. Meissner, N. Raimundo, R. Fernandez-Busnadiego, I. Dudanova

This study shows that amyloid-like aggregates impair lysosomal function in neurons by sequestering AP-31, leading to neurotoxicity.

bioRxiv · Dec 16, 2019 · PreprintCell Biology