R. Klein

CD4+ and CD8+ T cells are required to prevent SARS-CoV-2 persistence in the nasal compartment

This study shows that CD4+ and CD8+ T cells are necessary to prevent SARS-CoV-2 persistence in the nasal compartment but not in the lungs.

Interaction of adenylate cyclase CyaC with regulators Smc01817 and Clr of Sinorhizobium meliloti: cAMP as an ON/OFF trigger in sensor-regulator complexes?

Environmental DNA from archived leaves reveals widespread temporal turnover and biotic homogenization in forest arthropod communities

The paper uses environmental DNA from archived leaves to show temporal turnover and biotic homogenization in forest arthropod communities, not widespread declines in diversity.

Molecular diet analysis in zebra and quagga mussels (Dreissena spp.) and an assessment of the utility of aquatic filter feeders as biological eDNA filters

The paper develops primers to analyze mussel diets and assess their role in filtering eDNA, showing they reflect plankton diversity and can detect pathogens.

Amyloid-like aggregates cause lysosomal defects in neurons via gain-of-function toxicity

This study shows that amyloid-like aggregates impair lysosomal function in neurons by sequestering AP-31, leading to neurotoxicity.

In Silico Identification and In Vitro Validation of Novel KPC-2 β-lactamase Inhibitors

This study identifies and validates novel non-β-lactam inhibitors of KPC-2 β-lactamase through in silico screening and in vitro testing, showing one compound reduces meropenem MIC by fourfold.