The 3-Dimensional Genome Drives the Evolution of Asymmetric Gene Duplicates via Enhancer Capture-Divergence
U. Lee, D. Arsala, S. Xia, C. Li, M. Ali, N. Svetec, C. Langer, D. Sobreira, I. Eres, D. Sosa, J. Chen, L. Zhang, P. Reilly, A. Guzzetta, J. J. Emerson, , M. Long
This paper shows that enhancer capture-divergence (ECD) is a significant evolutionary mechanism for asymmetric, distally duplicated genes, using Drosophila HP6/Umbrea as an example.
bioRxiv · Nov 30, 2022 · PreprintEvolutionary Biology