Author

A. Guzzetta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Organism:Drosophila· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

D. Arsala· 2 shared D. Sosa· 2 shared J. Chen· 2 shared M. Long· 2 shared S. Xia· 2 shared B. Shen· 1 shared C. Langer· 1 shared C. Li· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersEvolutionary Biology

D. Arsala

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2 papers

Recent·Most cited

Evolutionarily new genes in humans with disease phenotypes reveal functional enrichment patterns shaped by adaptive innovation and sexual selection.

J. Chen, P. Landback, D. Arsala, A. Guzzetta, S. Xia, J. Atlas, D. Sosa, Y. Zhang, J. Cheng, B. Shen, M. Long

This study identifies evolutionarily new genes in humans with disease phenotypes, showing their enrichment in male reproductive diseases and adaptive traits like brain size and color vision.

bioRxiv · Nov 14, 2023Evolutionary Biology

The 3-Dimensional Genome Drives the Evolution of Asymmetric Gene Duplicates via Enhancer Capture-Divergence

U. Lee, D. Arsala, S. Xia, C. Li, M. Ali, N. Svetec, C. Langer, D. Sobreira, I. Eres, D. Sosa, J. Chen, L. Zhang, P. Reilly, A. Guzzetta, J. J. Emerson, , M. Long

This paper shows that enhancer capture-divergence (ECD) is a significant evolutionary mechanism for asymmetric, distally duplicated genes, using Drosophila HP6/Umbrea as an example.

bioRxiv · Nov 30, 2022 · PreprintEvolutionary Biology