Author

I. Kurth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:CITE-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Barlas· 1 shared A. Cercek· 1 shared A. E. Hendifar· 1 shared A. J. McRee· 1 shared A. Kremer· 1 shared B. Asselbergh· 1 shared C. Andreu-Agullo· 1 shared C. Kuppe· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Barlas

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Therapeutic targeting of SLC6A8 creatine transporter inhibits KRAS mutant and wildtype colon cancer and modulates human creatine levels

I. Kurth, N. Yamaguchi, C. Andreu-Agullo, H. S. Tian, S. Sridhar, S. Takeda, F. C. Gonsalves, J. M. Loo, A. Barlas, K. Manova-Todorova, R. Busby, J. C. Bendell, J. Strauss, M. Fakih, A. J. McRee, , S. F. Tavazoie

RGX-202 inhibits CRC growth by targeting SLC6A8 creatine transporter, reduces creatine and ATP levels, and shows efficacy in multiple tumor models and human trials.

bioRxiv · Apr 26, 2021Cancer Biology

Dissecting CD8+ T cell pathology of severe SARS-CoV-2 infection by single-cell epitope mapping

F. Schreibing, M. Hannani, F. Ticconi, E. Fewings, J. S. Nagai, M. Begemann, C. Kuppe, I. Kurth, J. Kranz, D. Frank, T. M. Anslinger, P. Ziegler, T. Kraus, J. Enczmann, V. Balz, , R. Kramann

This study identifies an immunogenic CD8+ T cell epitope associated with severe SARS-CoV-2 infection and characterizes its pathological features.

bioRxiv · Mar 3, 2021 · PreprintImmunology

Sensory neuropathy-causing mutations in ATL3 cause aberrant ER membrane tethering

M. Krols, S. Detry, B. Asselbergh, L. Almeida-Souza, A. Kremer, S. Lippens, R. de Rycke, V. De Winter, F.-J. Müller, I. Kurth, H. T. McMahon, S. N. Savvides, V. Timmerman, S. Janssens

This study shows that mutations in ATL3 cause aberrant ER membrane tethering, disrupting ER network organization and contributing to sensory neuropathy.

bioRxiv · Apr 5, 2018Cell Biology