Author

I. L. Urbatsch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Mezzell· 1 shared A. Moeller· 1 shared B. J. Loughlin· 1 shared C. G. Brouillette· 1 shared C. Wang· 1 shared D. Januliene· 1 shared D. R. Wetmore· 1 shared D. Waghray· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

A. Mezzell

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintOct 10, 2022

Mechanism of dual pharmacological correction and potentiation of human CFTR

C. Wang, Z. Yang, B. J. Loughlin…·J. F. Hunt

This paper uses cryo-EM to reveal how VX445 corrects CFTR folding and gating defects by altering allosteric communication pathways.

DOI 10.1101/2022.10.10.510913

𝕏 PostBluesky

BiophysicsbioRxivPreprintApr 28, 2022

Tracing the substrate translocation mechanism in P-glycoprotein

T. Gewering, D. Waghray, K. Parey…·Q. Zhang

This study reveals the substrate translocation mechanism in P-glycoprotein by determining cryoEM structures and using molecular dynamics simulations to identify conformational changes in TM1 that regulate transport.

DOI 10.1101/2022.04.28.489897

cryo-EMexperimental assay

𝕏 PostBluesky