Author

I. Litvan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Assay:flow cytometry· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Frazier· 3 shared A. Sette· 3 shared D. Sulzer· 3 shared J. G. Goldman· 3 shared R. N. Alcalay· 3 shared A. W. Amara· 2 shared C. S. Lindestam Arlehamn· 2 shared D. G. Standaert· 2 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

A. Frazier

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Author profile →

3 papers

Recent·Most cited

PINK1 is a target of T cell responses in Parkinson's disease

G. P. Williams, T. Michaelis, J. Rodrigues Lima-Junior, A. Frazier, N. K. Tran, E. J. Phillips, S. A. Mallal, I. Litvan, J. G. Goldman, R. N. Alcalay, J. Sidney, D. Sulzer, A. Sette, C. S. Lindestam Arlehamn

The paper identifies PINK1 as an autoantigen targeted by T cells in Parkinson's disease, with reactivity predominantly observed in male patients.

bioRxiv · Feb 9, 2024Immunology

Unaltered T cell responses to common antigens in individuals with Parkinson's disease

G. P. Williams, K. Muskat, A. Frazier, Y. Xu, J. Mateus, A. Grifoni, R. d. S. Antunes, D. Weiskopf, A. W. Amara, D. G. Standaert, J. G. Goldman, I. Litvan, R. N. Alcalay, D. Sulzer, C. S. L. Arlehamn, A. Sette

This study compares T cell responses to common antigens in Parkinson's disease patients and healthy controls, finding no significant differences in antigen-specific T cell activation or cytokine production.

bioRxiv · Apr 5, 2022Immunology

Transcriptional analysis of peripheral memory T cells reveals Parkinson's disease-specific gene signatures

R. Dhanwani, J. Rodrigues Lima-Junior, A. Sethi, J. Pham, G. Williams, A. Frazier, Y. Xu, A. W. Amara, D. G. Standaert, J. G. Goldman, I. Litvan, R. N. Alcalay, B. Peters, D. Sulzer, C. S. Lindestam Arlehamn, A. Sette

The paper identifies PD-specific gene signatures in peripheral memory T cells by analyzing RNA-seq data from PD patients and healthy controls.

bioRxiv · May 28, 2021Immunology