Multimodal engineering of extracellular vesicles for efficient intracellular protein delivery
X. Liang, D. Gupta, J. Xie, E. V. Wonterghem, L. V. Hoecke, J. Hean, Z. Niu, O. P. B. Wiklander, W. Zheng, R. J. Wiklander, R. He, D. R. Mamand, J. Bost, G. Zhou, H. Zhou, , S. EL Andaloussi
This paper develops VEDIC and VFIC systems for efficient intracellular protein delivery using engineered extracellular vesicles, achieving high recombination and genome editing efficiency in vitro and in vivo.
bioRxiv · Apr 30, 2023 · PreprintBioengineering