Immunogenicity and protective efficacy of a highly thermotolerant, trimeric SARS-CoV-2 receptor binding domain derivative
S. K. Malladi, U. R. Patel, R. S. Rajmani, R. Singh, S. Pandey, S. Kumar, S. Khaleeq, P. J. v. Vuren, S. S. Riddell, S. Goldie, S. Gayathri, D. Chakraborty, P. Kalita, I. Pramanick, N. Agarwal, , R. Varadarajan
This study designs a thermotolerant trimeric RBD vaccine candidate that elicits strong neutralizing antibodies against multiple SARS-CoV-2 variants in animal models.
bioRxiv · Jan 13, 2021Microbiology