P. Reddy

A redox cycle with complex II promotes sulfide quinone oxidoreductase dependent H2S oxidation

The paper identifies a redox cycle involving complex II and SQOR that sustains H2S oxidation when complex IV is inhibited, improving H2S clearance in cells exposed to microbiota-derived H2S.

Comparative immunogenicity of bacterially expressed soluble trimers and nanoparticle displayed influenza hemagglutinin stem immunogens

This study compares the immunogenicity of soluble trimeric influenza stem domain immunogens and nanoparticle-displayed versions, showing similar protection against homologous and heterologous viral challenges.

Immunogenicity and protective efficacy of a highly thermotolerant, trimeric SARS-CoV-2 receptor binding domain derivative

This study designs a thermotolerant trimeric RBD vaccine candidate that elicits strong neutralizing antibodies against multiple SARS-CoV-2 variants in animal models.

Design of a highly thermotolerant, immunogenic SARS-CoV-2 spike fragment

This paper designs a thermotolerant, immunogenic SARS-CoV-2 RBD protein fragment that is stable at high temperatures and elicits neutralizing antibodies in guinea pigs.

RNA-seq of Human T-Cells After Hematopoietic Stem Cell Transplantation Identifies Linc00402 as a Novel Regulator of T-Cell Alloimmunity

The paper identifies Linc00402 as a novel lncRNA regulating allogeneic T-cell responses through RNA-seq analysis of human T-cells post-HSCT.

Mitochondrial Complex II In Intestinal Epithelial Cells Regulates T-cell Mediated Immunopathology

This study identifies mitochondrial complex II disruption in intestinal epithelial cells as a key driver of T-cell mediated intestinal immunopathology across multiple disease models.

The ER cargo receptor SURF4 facilitates efficient erythropoietin secretion

This study identifies SURF4 as an ER cargo receptor that facilitates EPO secretion and suggests its modulation could treat erythropoiesis disorders.