Author

H.-S. Yi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. Shong· 3 shared A. Barros· 2 shared A. Neves-Costa· 2 shared D. Pedroso· 2 shared E. Seixas· 2 shared H. G. Colaco· 2 shared L. F. Moita· 2 shared T. R. Velho· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersImmunology

M. Shong

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Dose-response relationship for the resistance of human insulin to degradation by insulin-degrading enzyme

M. Okumura, T. Kuramochi, Y. Lin, R. Furukawa, K. Mizutani, T. Yokoyama, M. Kim, M. H. Lim, H.-S. Yi, K. Arai, H. Yamaguchi, H. Hojo, M. Iwaoka, Y. Tanaka, S.-Y. Park, , Y.-H. Lee

The paper investigates how human insulin resistance to degradation by IDE varies with dose and identifies structural features of the insulin hexamer that influence degradation kinetics without zinc.

bioRxiv · Apr 8, 2023 · PreprintBiochemistry

Loss-of-SIRT7 sensitizes hepatocellular carcinoma to sorafenib through the regulation of ERK Phosphorylation

Y. Kim, K.-Y. Jung, Y. H. Kim, P. Xu, Y. Jo, B. E. Kang, N. Pandit, J. Kwon, K. Gariani, J. Gariani, J. Lee, J. Verbeek, S. Nam, S.-J. Bae, K.-T. Ha, , J. Auwerx

This study shows that SIRT7 contributes to sorafenib resistance in HCC by enhancing ERK phosphorylation, and inhibiting SIRT7 with sorafenib reduces tumor growth.

bioRxiv · Mar 13, 2023 · PreprintCancer Biology

Host-dependent induction of disease tolerance to infection by tetracycline antibiotics

H. G. Colaco, A. Barros, A. Neves-Costa, E. Seixas, D. Pedroso, T. R. Velho, K. Willmann, H.-S. Yi, M. Shong, V. Benes, S. Weis, T. Köcher, L. F. Moita

This study shows tetracycline antibiotics protect against sepsis by inducing disease tolerance through mitochondrial protein synthesis inhibition, independent of their direct antibiotic effects.

bioRxiv · Nov 7, 2019Immunology

CXCL5-mediated recruitment of neutrophils into the peritoneal cavity of Gdf15-deficient mice protects against abdominal sepsis

I. Santos, H. G. Colaco, A. Neves-Costa, E. Seixas, T. R. Velho, D. Pedroso, A. Barros, R. Martins, S. Weiss, D. Payen, S. Weiss, H.-S. Yi, M. Shong, L. F. Moita

This study shows that GDF15 deficiency in mice protects against abdominal sepsis by enhancing CXCL5-mediated neutrophil recruitment to the peritoneum, improving bacterial control.

bioRxiv · Aug 12, 2019Immunology