Author

I. Setliff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

I. S. Georgiev· 2 shared N. Raju· 2 shared A. A. Murji· 1 shared A. Baum· 1 shared A. Bukreyev· 1 shared A. R. Shiakolas· 1 shared C. A. Kyratsous· 1 shared C. Scheepers· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

I. S. Georgiev

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Viral population genomics reveals host and infectivity impact on SARS-CoV-2 adaptive landscape

K. Gayvert, R. Copin, S. McKay, I. Setliff, W. K. Lim, A. Baum, C. A. Kyratsous, G. S. Atwal

The paper analyzes SARS-CoV-2 genomic diversity to identify sites under selection, showing purifying selection dominates with some diversifying pressure, particularly in the spike protein and T cell epitopes.

bioRxiv · Dec 30, 2021 · PreprintEvolutionary Biology

Efficient discovery of potently neutralizing SARS-CoV-2 antibodies using LIBRA-seq with ligand blocking

A. R. Shiakolas, N. Johnson, K. J. Kramer, N. Suryadevara, D. Wrapp, S. Periasamy, K. A. Pilewski, N. Raju, R. Nargi, R. E. Sutton, L. Walker, I. Setliff, J. E. Crowe, A. Bukreyev, R. H. Carnahan, , I. S. Georgiev

This study demonstrates that integrating ligand blocking into LIBRA-seq improves the efficiency of identifying potent SARS-CoV-2 neutralizing antibodies.

bioRxiv · Jun 2, 2021 · PreprintImmunology

Sequence and functional characterization of a public HIV-specific antibody clonotype

A. A. Murji, N. Raju, J. S. Qin, H. Kaldine, K. Janowska, E. F. Fechter, R. Mapengo, C. Scheepers, I. Setliff, P. Acharya, L. Morris, I. S. Georgiev

The paper characterizes a public HIV-specific antibody clonotype from three individuals, showing that antigen specificity is modulated by VH germline genes and that non-native heavy-light chain pairings maintain consistent antigen recognition.

bioRxiv · May 14, 2021Immunology