Author

I. Wallace

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

K. N. Swatek· 2 shared A. Clancy· 1 shared A. Knebel· 1 shared B. A. Schulman· 1 shared C. Johnson· 1 shared D. Kwasna· 1 shared E. V. Rusilowicz-Jones· 1 shared F. Lamoliatte· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

K. N. Swatek

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ISGylation-independent protection of cell growth by USP18 following interferon stimulation

A. Clancy, E. V. Rusilowicz-Jones, I. Wallace, K. N. Swatek, S. Urbe, M. J. Clague

This study shows USP18 suppresses ISG15 E1 enzyme expression and cell growth inhibition in interferon-stimulated cells independently of its deubiquitylase activity.

bioRxiv · Jul 21, 2023 · PreprintCell Biology

Insights into the ISG15 transfer cascade by the UBE1L activating enzyme

I. Wallace, K. Baek, J. R. Prabu, R. Vollrath, S. von Gronau, B. A. Schulman, K. N. Swatek

This study presents a cryo-EM structure of the UBE1L-UBE2L6 complex bound to ISG15, revealing mechanisms of ISG15 recognition and conjugation pathway specificity.

bioRxiv · Apr 6, 2023Biochemistry

Comprehensive approach to study branched ubiquitinchains reveals roles for K48-K63 branches inVCP/p97-related processes

S. M. Lange, M. R. McFarland, F. Lamoliatte, D. Kwasna, L. Shen, I. Wallace, I. Cole, L. A. Armstrong, A. Knebel, C. Johnson, V. De Cesare, Y. Kulathu

This paper develops a pipeline to study branched ubiquitin chains, identifies debranching enzymes, and reveals their roles in VCP/p97 processes and DNA damage responses.

bioRxiv · Jan 10, 2023Biochemistry