ImmunologybioRxivPreprint
State-dependent protein-protein interactions mediating 4-1BB CAR Signaling
S. A. Ritmeester-Loy, J. D. Lautz, Y. Zhang-Wong…·S. E. Smith
The paper identifies a network of protein interactions activated by 4-1BB CARs upon target engagement and shows that network activation magnitude correlates with IL-2 secretion.
DOI 10.1101/2022.06.07.495180