Author

S. E. Smith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Evolutionary Biology· 1 Immunology· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:proteomics· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Organism:yeast· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2

Frequent Co-Authors

S. L. Jaspersen· 3 shared B. D. Slaughter· 2 shared D. Tsuchiya· 2 shared J. R. Unruh· 2 shared J. Unruh· 2 shared Z. Yu· 2 shared A. C. Keene· 1 shared A. L. Wilson· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersCell Biology

S. L. Jaspersen

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Defining a core configuration for human centromeres during mitosis

A. S. Gupta, C. Seidel, D. Tsuchiya, S. A. McKinney, Z. Yu, S. E. Smith, J. Unruh, J. Gerton

The paper uses ChIP-seq and microscopy to determine the 3D organization of centromere components, revealing a core configuration that explains how centromeres function during mitosis.

bioRxiv · May 10, 2023 · PreprintCell Biology

State-dependent protein-protein interactions mediating 4-1BB CAR Signaling

S. A. Ritmeester-Loy, J. D. Lautz, Y. Zhang-Wong, J. A. Gustafson, A. L. Wilson, C. Lin, P. R. Gafken, M. C. Jensen, R. Orentas, S. E. Smith

The paper identifies a network of protein interactions activated by 4-1BB CARs upon target engagement and shows that network activation magnitude correlates with IL-2 secretion.

bioRxiv · Jun 7, 2022 · PreprintImmunology

The SEEL Motif and Members of the MYB-related REVEILLE Transcription Factor Family are Important for the Expression of LORELEI in the Synergid Cells of the Arabidopsis Female Gametophyte

J. A. Noble, A. Seddon, S. Uygun, S. E. Smith, S.-H. Shiu, R. Palanivelu

bioRxiv · Aug 17, 2021Plant Biology

A distinct inner nuclear membrane proteome in Saccharomyces cerevisiae gametes

S. N. Shelton, S. E. Smith, J. R. Unruh, S. L. Jaspersen

The paper identifies a distinct inner nuclear membrane proteome in yeast gametes, showing unique gene expression and protein composition compared to mitotic cells.

bioRxiv · Aug 2, 2021Cell Biology

A novel therapeutic antibody screening method using bacterial high-content imaging reveals functional antibody binding phenotypes of Escherichia coli ST131

M. Maes, Z. A. Dyson, S. E. Smith, D. A. Goulding, C. Ludden, S. Baker, P. Kellam, S. T. Reece, G. Dougan, J. Bartholdson Scott

This study uses high-content imaging to screen a monoclonal antibody against E. coli ST131 isolates, identifying four binding phenotypes and linking them to genetic variations affecting O-antigen structure.

bioRxiv · May 22, 2020Microbiology

Repeated evolution of circadian clock dysregulation in cavefish populations

K. L. Mack, J. B. Jaggard, J. L. Persons, C. N. Passow, B. A. Stanhope, E. Ferrufino, D. Tsuchiya, S. E. Smith, B. D. Slaughter, J. E. Kowalko, N. Rohner, A. C. Keene, S. E. McGaugh

This study shows that cavefish populations have independently evolved circadian clock dysregulation, with reduced transcriptome rhythmicity and sleep reduction linked to specific gene mutations.

bioRxiv · Jan 14, 2020Evolutionary Biology

Asi1 regulates the distribution of proteins at the inner nuclear membrane in Saccharomyces cerevisiae

C. J. Smoyer, S. E. Smith, S. McCroskey, J. Unruh, S. L. Jaspersen

This study shows Asi1 regulates INM protein distribution by removing mis-targeted proteins and controlling native components like Pom33 through ubiquitination.

bioRxiv · Oct 14, 2018Cell Biology

Membrane insertion function for SUN-KASH complex revealed by high resolution analysis of yeast centrosomes

J. Chen, J. M. Gardner, Z. Yu, S. E. Smith, S. McKinney, B. D. Slaughter, J. R. Unruh, S. L. Jaspersen

The paper uses high-resolution imaging to reveal the structure and function of the SUN-KASH complex in yeast centrosome insertion, identifying Mps3 as a fifth SPIN component and a novel LINC complex.

bioRxiv · Sep 10, 2018Cell Biology