Author

S. Bose

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 2 Microbiology· 2 Biophysics· 1 Cell Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 9 Assay:bulk RNA-seq· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2

Frequent Co-Authors

A. Berchuck· 1 shared A. Dutta· 1 shared A. Gopinath· 1 shared A. J. Wisdom· 1 shared A. Pande· 1 shared A. Paz· 1 shared B. M. Spiegelman· 1 shared C. D. Kontos· 1 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 3 mutual co-author links

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1 shared paperCancer Biology

A. Berchuck

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

A chemically-induced attenuated strain of Candida albicans generates robust protective immune responses and prevents systemic candidiasis development

S. Bose, S. R. Sahu, A. Dutta, N. Acharya

The paper attenuates Candida albicans using EDTA to create a live vaccine candidate that induces protective immunity and prevents systemic candidiasis in mice.

bioRxiv · Nov 3, 2023 · PreprintMicrobiology

Novel Function of Transcription Factor TTF1 in UV Mediated DNA Damage Repair in Mammalian Cells

K. Tiwari, S. Bose, N. Mishra, S. K. Singh

This study identifies TTF1 as an interactor of DDB1 and shows its role in UV-induced DNA damage repair through co-localization with γH2AX and reciprocal regulation of DDB1 levels.

bioRxiv · May 9, 2023 · PreprintBiochemistry

Biochemical characterization of a GDP-mannose transporter from Chaetomium thermophilum

G. T. R. Premageetha, K. Dhanabalan, S. Bose, L. Manjunath, D. Joseph, A. Paz, S. Grandfield, V. Nayak, L. M. Bredeston, J. Abramson, R. Subramanian

The paper characterizes CtVrg4, a GDP-mannose transporter from Chaetomium thermophilum, showing enhanced thermal stability and phosphatidylinositol lipid binding.

bioRxiv · Jan 13, 2023 · PreprintBiochemistry

RBM43 links adipose inflammation and energy expenditure through translational regulation of PGC1alpha

P. A. Dumesic, S. E. Wilensky, S. Bose, J. G. Van Vranken, S. P. Gygi, B. M. Spiegelman

This study identifies RBM43 as a regulator of PGC1alpha translation, linking adipose inflammation to reduced energy expenditure and mitochondrial function in obesity.

bioRxiv · Jan 6, 2023 · PreprintCell Biology

G6PD Inhibition Sensitizes Ovarian Cancer Cells to Oxidative Stress in the Metastatic Omental Microenvironment

S. Bose, Q. Huang, Y. Ma, L. Wang, G. O. Rivera, Y. Ouyang, R. Whitaker, R. A. Gibson, C. D. Kontos, A. Berchuck, R. Previs, X. Shen

This study shows G6PD inhibition increases oxidative stress and reduces omental metastases in ovarian cancer.

bioRxiv · Apr 20, 2022Cancer Biology

Opportunistic gut sampling indicates differential diet and plastic ingestion risk in Indian dugongs

S. Prajapati, C. Ghanekar, S. Pathan, R. Shekar, K. M. Magesh, S. Gole, S. Bose, S. Iyer, A. Pande, J. A. Johnson, S. Kuppusamy

The paper analyzes gut contents of stranded Indian dugongs to compare seagrass diet and plastic ingestion risk between Tamil Nadu and Gujarat.

bioRxiv · Aug 11, 2021 · PreprintEcology

Proinflammatory responses in SARS-CoV-2 infected and soluble spike glycoprotein S1 subunit activated human macrophages

K. Chiok, K. Hutchison, L. G. Miller, S. Bose, T. A. Miura

This study shows that soluble SARS-CoV-2 Spike S1 subunit activates human macrophages to produce pro-inflammatory mediators, independent of viral replication.

bioRxiv · Jun 14, 2021Immunology

Substrate mediated elastic coupling between motile cells modulates inter-cell interactions and enhances cell-cell contact

S. Bose, K. Dasbiswas, A. Gopinath

The paper builds a biophysical model to study how substrate deformation mediates cell-cell interactions and influences collective cell behavior during migration.

bioRxiv · Mar 6, 2021Biophysics

Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion

S. Ding, R. Zang, J. B. Case, M. F. Gomez Castro, Z. Liu, Q. Zeng, H. Zhao, J. Son, P. W. Rothlauf, G. Hou, S. Bose, X. Wang, M. D. Vahey, T. Kirchhausen, D. H. Fremont, , S. P. J. Whelan

The paper identifies CH25H and its product 25HC as inhibitors of SARS-CoV-2 replication by blocking membrane fusion.

Proceedings of the National Academy of Sciences · Nov 25, 2020Peer-reviewedMicrobiology

The Na+/K+ ATPase Regulates Glycolysis and Modifies Immune metabolism in Tumors

S. M. Sanderson, Z. Xiao, A. J. Wisdom, S. Bose, M. V. Liberti, M. A. Reid, E. Hocke, S. G. Gregory, D. G. Kirsch, J. W. Locasale

This study shows that Na+/K+ ATPase inhibition via digoxin disrupts glycolysis in tumor and healthy cells, alters immune metabolism, and changes tumor microenvironment composition.

bioRxiv · Mar 31, 2020 · PreprintCancer Biology