MicrobiologybioRxiv
A widely distributed gene cluster compensates for uricase loss in hominids
Y. Liu, J. B. Jarman, Y. S. Low…·D. Dodd
The paper identifies a bacterial gene cluster that compensates for human uricase loss by degrading uric acid in the gut, linking gut microbiota to hyperuricemia and gout risk.
DOI 10.1016/j.cell.2023.06.010