Author

J. B. Mackey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:human· 1

Frequent Co-Authors

F. Fercoq· 3 shared L. M. Carlin· 3 shared A. J. McFarlane· 2 shared C. Nixon· 2 shared D. Whyte· 2 shared E. W. Roberts· 2 shared J. C. Norman· 2 shared K. Blyth· 2 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

F. Fercoq

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Uridine Phosphorylase-1 supports metastasis of mammary cancer by altering immune and extracellular matrix landscapes of the lung

D. Whyte, J. Vande Voorde, D. Sumpton, S. Dhayade, E. Dornier, M. Moore, D. Novo, J. Peters, R. Wiesheu, J. B. Mackey, A. J. McFarlane, F. Fercoq, S. Fisher, C. Dehesa Caballero, K. Gilroy, , C. J. Clarke

bioRxiv · Jul 2, 2024 · PreprintCancer Biology

Integrin conformation-dependent neutrophil slowing obstructs the capillaries of the pre-metastatic lung in a model of breast cancer

F. Fercoq, G. S. Cairns, M. De Donatis, J. B. Mackey, A. Floerchinger, A. J. McFarlane, X. L. Raffo-Iraolagoitia, D. Whyte, L. W. Arnott, C. Nixon, R. Wiesheu, L. Brown, S. Al-Khalidi, J. C. Norman, E. W. Roberts, , L. M. Carlin

This study shows that integrin conformation-dependent neutrophil slowing in pre-metastatic lungs obstructs capillaries and may contribute to immunosuppression in breast cancer.

bioRxiv · Mar 19, 2024Immunology

Multimodal decoding of human liver regeneration

K. P. Matchett, J. W. Wilson-Kanamori, J. R. Portman, A. Kapourani, F. Fercoq, S. May, J. B. Mackey, M. Brice, E. Zajdel, M. Beltran-Sierra, E. F. Sutherland, G. C. Wilson, S. J. Wallace, L. Kitto, N. T. Younger, , N. C. Henderson

This study uses single-nuclei RNA sequencing and spatial profiling to create a single-cell atlas of human liver regeneration, identifying a novel migratory hepatocyte subpopulation and demonstrating that wound closure precedes hepatocyte proliferation.

bioRxiv · Feb 24, 2023Cell Biology