Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
D. Whyte, J. Vande Voorde, D. Sumpton, S. Dhayade, E. Dornier, M. Moore, D. Novo, J. Peters, R. Wiesheu, J. B. Mackey, A. J. McFarlane, F. Fercoq, S. Fisher, C. Dehesa Caballero, K. Gilroy, , C. J. Clarke
bioRxiv · Jul 2, 2024 · PreprintCancer Biology
F. Fercoq, G. S. Cairns, M. De Donatis, J. B. Mackey, A. Floerchinger, A. J. McFarlane, X. L. Raffo-Iraolagoitia, D. Whyte, L. W. Arnott, C. Nixon, R. Wiesheu, L. Brown, S. Al-Khalidi, J. C. Norman, E. W. Roberts, , L. M. Carlin
This study shows that integrin conformation-dependent neutrophil slowing in pre-metastatic lungs obstructs capillaries and may contribute to immunosuppression in breast cancer.
bioRxiv · Mar 19, 2024Immunology
X. L. Raffo-Iraolagoitia, A. J. McFarlane, B. Kruspig, F. Fercoq, J. Secklehner, M. De Donatis, J. B. G. Mackey, R. Wiesheu, S. Laing, Y.-C. Hsieh, R. Shaw, R. Corbyn, C. Nixon, C. Miller, K. Kirschner, , L. M. Carlin
The paper identifies that CD27+ γδ T cells impair the differentiation of tumor-associated macrophages into airway macrophages in lung adenocarcinoma.
bioRxiv · Sep 14, 2023Immunology
K. P. Matchett, J. W. Wilson-Kanamori, J. R. Portman, A. Kapourani, F. Fercoq, S. May, J. B. Mackey, M. Brice, E. Zajdel, M. Beltran-Sierra, E. F. Sutherland, G. C. Wilson, S. J. Wallace, L. Kitto, N. T. Younger, , N. C. Henderson
This study uses single-nuclei RNA sequencing and spatial profiling to create a single-cell atlas of human liver regeneration, identifying a novel migratory hepatocyte subpopulation and demonstrating that wound closure precedes hepatocyte proliferation.
bioRxiv · Feb 24, 2023Cell Biology
A. Santi, E. J. Kay, L. J. Neilson, L. McGarry, S. Lilla, M. Mullin, N. R. Paul, F. Fercoq, G. Koulouras, G. Rodriguez-Blanco, D. Athineos, S. Mason, M. Hughes, Y. Kieffer, C. Nixon, , S. Zanivan
CAFs with a myofibroblastic-like phenotype transfer proteins to ECs, including plasma membrane receptors, through matrix-bound EVs.
bioRxiv · Jan 13, 2023 · PreprintCancer Biology
R. J. Hewitt, F. Puttur, D. C. A. Gaboriau, F. Fercoq, M. Fresquet, W. J. Traves, L. L. Yates, S. A. Walker, P. L. Molyneaux, S. V. Kemp, A. G. Nicholson, A. Rice, R. Lennon, L. M. Carlin, A. J. Byrne, , C. M. Lloyd
This study shows that changes in the extracellular matrix in IPF affect KRT5+ basal cell migration and function, contributing to lung fibrosis.
bioRxiv · Dec 16, 2022Cell Biology
J. Leslie, J. B. G. Mackey, T. Jamieson, E. Ramon-Gil, T. M. Drake, F. Fercoq, W. Clark, K. Gilroy, A. Hedley, C. Nixon, S. Luli, M. Laszczewska, R. Pinyol, R. Esteban-Fabro, C. E. Willoughby, , Carlin
This study shows that combining CXCR2 inhibition with anti-PD1 therapy enhances immunotherapy response in NASH-HCC by reprogramming tumor-associated neutrophils.
bioRxiv · Feb 24, 2022Cancer Biology
J. B. G. Mackey, A. J. McFarlane, T. Jamieson, R. Jackstadt, X. L. Raffo-Iraolagoitia, J. Secklehner, X. Cortes-Lavaud, F. Fercoq, W. Clarke, A. Hedley, K. Gilroy, S. Lilla, J. Vuononvirta, G. J. Graham, K. De Filippo, , L. M. Carlin
This study identifies Ly6G expression levels as a marker for neutrophil maturation stages and shows spleen-derived neutrophils mature faster with distinct transcriptional profiles.
bioRxiv · Jul 21, 2021 · PreprintImmunology
J. McCowan, P. M. Kirkwood, F. Fercoq, W. T'Jonck, C. M. Mawer, R. Cunningham, A. S. Mirchandani, A. M. Hoy, G.-R. Jones, C. G. Hansen, N. Hirani, S. J. Jenkins, S. Henri, B. Malissen, S. R. Walmsley, , C. C. Bain
This study identifies EGR2 as essential for the identity and function of alveolar macrophages in health and tissue repair.
bioRxiv · May 6, 2021Immunology