Plasmacytoid dendritic cell expansion defines a distinct subset of RUNX1 mutated acute myeloid leukemia
W. Xiao, A. Chan, M. R. Waarts, T. Mishra, Y. Liu, S. F. Cai, J. Yao, Q. Gao, R. L. Bowman, R. Koche, I. S. Csete, J. Baik, S. Yanis, C. Famulare, M. Patel, , R. Levine
This study identifies pDC-AML as a distinct AML subset with high RUNX1 mutations and pDC transcriptional features, suggesting CD123 targeting as a therapeutic strategy.
Blood · Mar 11, 2021Peer-reviewedPathology