Author

J. Bainbridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Hoeh· 1 shared A. Kalitzeos· 1 shared A. Leung· 1 shared A. Sacristan-Reviriego· 1 shared A. Smith· 1 shared A. Tufail· 1 shared A.-J. F. Carr· 1 shared B. Nommiste· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperPathology

A. Hoeh

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Translational readthrough as a potential therapeutic for AIPL1-associated Leber Congenital Amaurosis in a patient-derived iPSC-retinal organoid model

A. Leung, A. Sacristan-Reviriego, P. Perdigao, H. Sai, M. Georgiou, A. Kalitzeos, A.-J. F. Carr, P. J. Coffey, M. Michaelides, J. Bainbridge, M. E. Cheetham, J. van der Spuy

This study uses patient-derived iPSC-retinal organoids to investigate translational readthrough as a therapy for LCA4 caused by AIPL1 mutations.

bioRxiv · Dec 17, 2021 · PreprintCell Biology

Spatiotemporal Control of Actomyosin Contractility by MRCKβ Signaling Drives Phagocytosis

C. Zihni, T. Georgiadis, C. Ramsden, E. Sanchez-heras, B. Nommiste, O. Semenyuk, J. Bainbridge, P. Coffey, A. Smith, R. Ali, M. Balda, K. Matter

This study identifies MRCKβ signaling as a key regulator of actomyosin contractility during phagocytosis, showing its role in membrane deformation and particle internalization.

bioRxiv · Mar 25, 2021Cell Biology

A Humanized Antibody against LRG1 that Inhibits Angiogenesis and Reduces Retinal Vascular Leakage

D. Kallenberg, V. Tripathi, F. Javaid, C. Pilotti, J. George, S. Davis, J. W. Blackburn, M. O'Connor, L. Dowsett, C. Bowers, S. E. Liyanage, M. Gourlaouen, A. Hoeh, F. Mota, D. Selwood, , S. E. Moss

bioRxiv · Jul 25, 2020 · PreprintPathology

Syndecan-4 is required for VE-Cadherin trafficking during pathological angiogenesis

G. De Rossi, M. Vähätupa, E. Cristante, S. Liyanage, U. May, L. Pellinen, S. Aittomäki, Z. Martinez Cordova, M. Pesu, H. Uusitalo-Järvinen, J. Bainbridge, T. Järvinen, J. Whiteford

This study shows Syndecan-4 is required for VE-Cadherin internalization during pathological angiogenesis and can inhibit angiogenic responses in disease models.

bioRxiv · Aug 19, 2019 · PreprintCell Biology