Author

J. Beer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2

Frequent Co-Authors

A. Ohnemus· 2 shared D. Schnepf· 2 shared M. Schwemmle· 2 shared A. Breithaupt· 1 shared A. Wack· 1 shared B. S. Trueeb· 1 shared B. Sachs· 1 shared B. Traenkle· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

A. Ohnemus

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2 papers

Recent·Most cited

Impaired immune response drives age-dependent severity of COVID-19

J. Beer, S. Crotta, A. Breithaupt, A. Ohnemus, J. Becker, B. Sachs, L. Kern, M. Llorian, N. Ebert, F. Labroussaa, T. T. N. Tran, B. S. Trueeb, J. Jores, V. Thiel, M. Beer, , D. Schnepf

This study identifies impaired interferon responses as a cause of age-dependent COVID-19 severity and shows that combined IFN-γ and IFN-λ therapy can mitigate disease in aged mice.

bioRxiv · Apr 21, 2022Immunology

A broadly neutralizing biparatopic Nanobody protects mice from lethal challenge with SARS-CoV-2 variants of concern

T. R. Wagner, D. Schnepf, J. Beer, K. Klingel, N. Ruetalo, P. D. Kaiser, D. Junker, M. Sauter, B. Traenkle, D. I. Frecot, M. Becker, N. Schneiderhan-Marra, A. Ohnemus, M. Schwemmle, M. Schindler, U. Rothbauer

This study identifies a biparatopic nanobody that protects mice from lethal SARS-CoV-2 infection and reduces viral load and inflammation.

bioRxiv · Aug 8, 2021 · PreprintBiochemistry