Author

F. Labroussaa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 5 Immunology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 4 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:rat· 2 Organism:chicken / avian· 1 Research Focus:clustering· 1

Frequent Co-Authors

J. Jores· 7 shared N. Ebert· 4 shared V. Thiel· 4 shared M. Beer· 3 shared R. Dijkman· 3 shared A. Breithaupt· 2 shared A. Taddeo· 2 shared B. Hoffmann· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

7 shared papersMicrobiology

J. Jores

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Temperature effects on the magnitude of the bovine ex vivo immune response towards Mycoplasmopsis bovis

T. Demoulins, T. Yimthin, D. Lindtke, L. Eggerschwiler, R. Siegenthaler, F. Labroussaa, J. Jores

This study examines how temperature affects the bovine immune response to Mycoplasmopsis bovis using ex vivo assays and identifies temperature-dependent changes in immune cell activation and cytokine secretion.

bioRxiv · Oct 16, 2023 · PreprintImmunology

Impaired immune response drives age-dependent severity of COVID-19

J. Beer, S. Crotta, A. Breithaupt, A. Ohnemus, J. Becker, B. Sachs, L. Kern, M. Llorian, N. Ebert, F. Labroussaa, T. T. N. Tran, B. S. Trueeb, J. Jores, V. Thiel, M. Beer, , D. Schnepf

This study identifies impaired interferon responses as a cause of age-dependent COVID-19 severity and shows that combined IFN-γ and IFN-λ therapy can mitigate disease in aged mice.

bioRxiv · Apr 21, 2022Immunology

Enhanced fitness of SARS-CoV-2 variant of concern B.1.1.7, but not B.1.351, in animal models

L. Ulrich, N. J. Halwe, A. Taddeo, N. Ebert, J. Schön, C. Devisme, B. S. Trüeb, B. Hoffmann, M. Wider, M. Bekliz, M. Essaidi-Laziosi, M. L. Schmidt, D. Niemeyer, V. M. Corman, A. Kraft, , C. Benarafa

The paper compares the fitness of SARS-CoV-2 variants B.1.1.7 and B.1.351 in animal models, finding B.1.1.7 has a fitness advantage in ferrets and mice but not in hamsters.

bioRxiv · Jun 28, 2021Microbiology

Minimalistic mycoplasmas harbor different functional toxin-antitoxin systems

V. Hill, H. Akarsu, R. S. Barbarroja, V. L. Cippa, M. Heller, L. Falquet, M. Heller, F. Labroussaa, J. Jores, M. H. Stoffel

This paper identifies and validates functional toxin-antitoxin systems in Mycoplasma mycoides subsp. capri, showing genomic plasticity and potential roles in persistence and stress tolerance.

bioRxiv · Jan 21, 2021 · PreprintMicrobiology

SARS-CoV-2 spike D614G variant confers enhanced replication and transmissibility

B. Zhou, T. T. N. Thao, D. Hoffmann, A. Taddeo, N. Ebert, F. Labroussaa, A. Pohlmann, J. King, J. Portmann, N. J. Halwe, L. Ulrich, B. S. Trueb, J. N. Kelly, X. Fan, B. Hoffmann, , M. Beer

This study shows the SARS-CoV-2 D614G variant has enhanced replication and transmissibility in animal models, explaining its global dominance.

bioRxiv · Oct 27, 2020Microbiology

Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform

T. T. N. Thao, F. Labroussaa, N. Ebert, P. V'kovski, H. Stalder, J. Portmann, J. Kelly, S. Steiner, M. Holwerda, A. Kratzel, M. Gultom, L. Laloli, L. Huesser, M. Wider, S. Pfaender, , V. Thiel

This paper describes a yeast-based synthetic genomics platform for rapid reconstruction of RNA viruses, including SARS-CoV-2, using synthetic DNA fragments and TAR cloning.

bioRxiv · Feb 21, 2020Microbiology

Removal of a subset of non-essential genes fully attenuates a highly virulent Mycoplasma strain

J. Jores, L. Ma, P. Ssajjakambwe, E. Schieck, A. M. Liljander, S. Chandran, M. H. Stoffel, V. L. Cippa, Y. Arfi, N. Asad-Garcia, L. Falquet, P. Sirand-Pugnet, A. Blanchard, C. Lartigue, H. Posthaus, , S. Vashee

This paper attenuates a highly virulent Mycoplasma strain by deleting non-essential genes and demonstrates its safety in vivo using a goat model.

bioRxiv · Jan 10, 2019Microbiology