Author

J. Boucher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Research Focus:ecology & biodiversity· 1

Frequent Co-Authors

C. A. Souders· 2 shared J. Gabriel· 2 shared A. Ager· 1 shared A. Ayyaz· 1 shared A. Brousseau· 1 shared A. Dehkharghani· 1 shared A. Leduc· 1 shared A. M. Doucette· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersImmunology

C. A. Souders

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The 2023 wildfire season in Quebec: an overview of extreme conditions, impacts, lessons learned and considerations for the future.

Y. Boulanger, D. Arseneault, A.-C. Belisle, Y. Bergeron, J. Boucher, Y. Boucher, V. Danneyrolles, S. Erni, P. Gachon, M. Girardin, E. Grant, P. Grondin, J.-P. Jette, G. Labadie, M. Leblond, , K. Waldron

The paper reviews the 2023 Quebec wildfire season, its extreme conditions, impacts on ecosystems and communities, and proposes strategies for future wildfire risk management.

bioRxiv · Feb 20, 2024Ecology

Alpaca Single B Cell Interrogation and Heavy-Chain-Only Antibody Discovery on an Optofluidic Platform

M. B. Shapiro, J. Boucher, A. Brousseau, A. Dehkharghani, J. Gabriel, V. Kamat, K. Patil, F. Gao, J. Walker, R. Kelly, C. A. Souders

This paper develops a method to discover heavy-chain-only antibodies from alpaca B cells using an optofluidic platform and validates PSMA-specific VHH candidates.

Antibody Therapeutics · Aug 17, 2023Peer-reviewedImmunology

In vivo CRISPR screens reveal Serpinb9 and Adam2 as regulators of immune therapy response in lung cancer

D. Dervovic, E. L. Y. Chen, A. Malik, S. Afiuni, J. Boucher, J. M. Berman, K. Teng, A. Ayyaz, Y. Lu, M. Narimatsu, G. Mbamalu, S. Loganathan, S. Martinez, R. Tsai, J.-B. Lee, , D. Schramek

The paper uses in vivo CRISPR screens to identify Serpinb9 and Adam2 as genes regulating immune therapy response in lung cancer, showing their roles in immune suppression and enhancement.

bioRxiv · Mar 13, 2022Cancer Biology

Accelerated Antibody Discovery Targeting the SARS-CoV-2 Spike Protein for COVID-19 Therapeutic Potential

T. E. Mullen, R. Abdullah, J. Boucher, A. S. Brousseau, N. K. Dasuri, N. T. Ditto, A. M. Doucette, C. Emery, J. Gabriel, B. Greamo, K. S. Patil, K. Rothenberger, J. Stolte, C. A. Souders

This study uses two in vivo approaches to rapidly discover antibodies targeting the SARS-CoV-2 spike protein, identifying candidates with distinct epitope binding and blocking activities.

Antibody Therapeutics · Aug 28, 2021Peer-reviewedImmunology

The eIF2α Kinase Heme Regulated Inhibitor (HRI) Protects The Host From Infection By Regulating Intracellular Pathogen Trafficking

W. Bahnan, J. Boucher, P. Gayle, N. Shrestha, M. Rosen, B. Aktas, B. Adkins, A. Ager, W. Khan, K. Schesser

This study shows that HRI protects against Listeria monocytogenes infection by restricting pathogen trafficking and antigen presentation.

bioRxiv · May 26, 2017Immunology