Author

K. Teng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:genetic perturbation / CRISPR· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:CRISPR screen· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Malik· 2 shared D. Schramek· 2 shared H. W. Jackson· 2 shared J. Wrana· 2 shared K. Harwalkar· 2 shared M. J. Ford· 2 shared N. Yamanaka· 2 shared R. Tsai· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

A. Malik

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

In vivo CRISPR screens reveal Serpinb9 and Adam2 as regulators of immune therapy response in lung cancer

D. Dervovic, E. L. Y. Chen, A. Malik, S. Afiuni, J. Boucher, J. M. Berman, K. Teng, A. Ayyaz, Y. Lu, M. Narimatsu, G. Mbamalu, S. Loganathan, S. Martinez, R. Tsai, J.-B. Lee, , D. Schramek

The paper uses in vivo CRISPR screens to identify Serpinb9 and Adam2 as genes regulating immune therapy response in lung cancer, showing their roles in immune suppression and enhancement.

bioRxiv · Mar 13, 2022Cancer Biology

Loss of epigenetic regulation disrupts lineage integrity, reactivatesmultipotency and promotes breast cancer

E. Langille, K. N. Al-Zahrani, Z. Ma, A. Malik, S. K. Loganathan, D. Trcka, J. Liu, K. Kozma, R. Tsai, K. Teng, R. Espin, S. Barutcu, T. Nguyen, R. Bremner, H. W. Jackson, , D. Schramek

This study identifies epigenetic regulators as tumor suppressors in breast cancer by showing their loss leads to lineage infidelity and reactivation of lactation programs.

bioRxiv · Oct 22, 2021 · PreprintCancer Biology

Modeling High-grade serous ovarian carcinoma using a combination of in vivo electroporation and CRISPR/Cas9 mediated genome editing

K. Teng, M. J. Ford, K. Harwalkar, Y. Li, D. Farnell, N. Yamanaka, T. N. Tuyet Nhung, D. G. Huntsman, J. Arseneau, Y. Yamanaka

This paper develops a method to generate HGSC mouse models using in vivo electroporation and CRISPR/Cas9, showing that specific gene mutations lead to different tumor characteristics.

bioRxiv · Mar 29, 2021Cancer Biology

Anatomical and cellular heterogeneity in the mouse oviduct-- its potential roles in reproduction and preimplantation development

K. Harwalkar, M. J. Ford, K. Teng, N. Yamanaka, B. Yang, I. Burtscher, H. Lickert, Y. Yamanaka

This study examines the anatomical and cellular structure of the mouse oviduct, identifying new features and roles in reproduction and preimplantation development.

bioRxiv · Aug 23, 2020Physiology