Author

J. C. Cheung

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1

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H. Wang· 1 shared J. Jiang· 1 shared M. Gellert· 1 shared N. d. Val· 1 shared T. Fox· 1 shared W. Yang· 1 shared X. Chen· 1 shared X. Xu· 1 shared

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2020-2020 · peak 1/yr

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1 shared paperBiochemistry

H. Wang

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1 paper

Recent·Most cited

BiochemistrybioRxivOct 19, 2020

Stretch and Twist of HEAT Repeats Leads to Activation of DNA-PK Kinase

X. Chen, X. Xu, Y. Chen…·W. Yang

The paper reports cryoEM structures of DNA-PKcs in inactive and activated forms, revealing structural changes in HEAT repeats that drive kinase activation.

DOI 10.1016/j.molcel.2020.12.015

cryo-EMexperimental assay

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