TCR convergence in individuals treated with immune checkpoint inhibition for cancer
T. Looney, D. Topacio-Hall, G. Lowman, J. Conroy, C. Morrison, D. Oh, L. Fong, L. Zhang
The paper compares TCR convergence detected by two sequencing platforms in cancer patients and finds Illumina-based sequencing shows higher convergence, which can be used to predict treatment response.
bioRxiv · Jun 14, 2019Cancer Biology