Author

J. Desai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Arastehfar· 1 shared A. D. Adamson· 1 shared A. Dhillon· 1 shared D. Perlin· 1 shared E. F. Lee· 1 shared E. Marinopoulou· 1 shared E. Shor· 1 shared F. Daneshnia· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Arastehfar

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A multidimensional assessment of in-host fitness costs of drug resistance in the opportunistic fungal pathogen Candida glabrata

A. Arastehfar, F. Daneshnia, H. Hovhannisyan, N. Cabrera, M. Ilkit, J. Desai, T. Gabaldon, E. Shor, D. Perlin

This study assesses the fitness costs of drug resistance in C. glabrata isolates across different host environments, showing reduced fitness in macrophages and gut but comparable fitness in the spleen.

bioRxiv · Jul 3, 2023 · PreprintMicrobiology

HES1 protein oscillations are necessary for neural stem cells to exit from quiescence

E. Marinopoulou, N. Sabherwal, V. Biga, J. Desai, A. D. Adamson, N. Papalopulu

This study shows that HES1 protein oscillations are necessary for neural stem cells to exit quiescence, while sustained HES1 expression does not affect entry into quiescence.

iScience · Oct 1, 2021Peer-reviewedCell Biology

Dual MAPK and HDAC inhibition rewires the apoptotic rheostat to trigger colorectal cancer cell death

L. J. Jenkins, I. Y. Luk, M. Palmieri, W. D. Fairlie, E. F. Lee, K. L. Schoffer, T. Tan, I. Ng, N. Vukelic, J. W. Tse, R. Nightingale, Z. Alam, G. Iatropoulos, M. Ernst, S. Afshar-Sterle, , J. M. Mariadason

This study shows that combining MEK/ERK and HDAC inhibition synergistically induces apoptosis in colorectal cancer cells and organoids, and can be tailored to specific MAPK genotypes.

bioRxiv · Feb 15, 2021 · PreprintCancer Biology