Cell BiologyProceedings of the National Academy of SciencesPeer-reviewed
Differential phase register of Hes1 oscillations with mitoses underlies cell-cycle heterogeneity in ER+ breast cancer cells.
N. Sabherwal, A. Rowntree, E. Marinopoulou…·N. Papalopulu
The paper investigates Hes1 oscillations in ER+ breast cancer cells, showing that phase shifts in these oscillations relative to mitosis correlate with cell-cycle length heterogeneity and cancer stem cell properties.
DOI 10.1073/pnas.2113527118