Author

J. Deveryshetty

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 4 Approach:experimental assay· 3 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Organism:yeast· 1

Frequent Co-Authors

B. Bothner· 3 shared E. Antony· 3 shared R. Chadda· 3 shared J. Mattice· 2 shared N. Pokhrel· 2 shared V. Kaushik· 2 shared A. Patterson· 1 shared A. S. Holehouse· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersBiochemistry

B. Bothner

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4 papers

Recent·Most cited

Wrapping of single-stranded DNA by Replication Protein A and modulation through phosphorylation

R. Chadda, V. Kaushik, I. M. Ahmad, J. Deveryshetty, A. S. Holehouse, S. T. d. Sigurdsson, B. Bothner, R. Dastvan, S. S. Origanti, E. Antony

This study uses single-molecule techniques to show that RPA partially wraps ssDNA and that phosphorylation at Ser-384 modulates this wrapping.

bioRxiv · Mar 28, 2024 · PreprintBiochemistry

Homodecameric Rad52 promotes single-position Rad51 nucleation in homologous recombination

J. Deveryshetty, R. Chadda, J. Mattice, S. Karunakaran, M. Rau, K. Basore, N. Pokhrel, N. Englander, J. Fitzpatrick, B. Bothner, E. Antony

This study reveals that homodecameric Rad52 facilitates single-position Rad51 nucleation in homologous recombination through specific structural and interaction features.

bioRxiv · Feb 5, 2023 · PreprintBiochemistry

Rtt105 configurationally staples RPA and blocks facilitated exchange and interactions with RPA-interacting proteins

S. Kuppa, J. Deveryshetty, R. Chadda, J. Mattice, N. Pokhrel, V. Kaushik, A. Patterson, N. Dhingra, S. Pangeni, M. K. Sadauskas, S. Shiekh, H. Balci, T. Ha, X. Zhao, B. Bothner, E. Antony

This study shows Rtt105 binds to RPA, staples it, and blocks RIP interactions without ssDNA, while stabilizing RPA-ssDNA filaments with ssDNA.

bioRxiv · Feb 5, 2022 · PreprintBiochemistry

Novel strand exchange activity of the human PALB2 DNA Binding Domain and its critical role for DNA repair in cells

J. Deveryshetty, M. Ryzhikov, N. Brahati, T. Peterlini, G. Dellaire, J.-Y. Masson, S. Korolev

The paper identifies a DNA-binding domain in PALB2 that enhances RAD51-mediated DNA repair and can promote strand exchange independently of RAD51.

bioRxiv · Jan 8, 2019Biochemistry