Structural basis of mammalian Complex IV inhibition by steroids
J. Di Trani, A. Moe, D. Riepl…·J. L. Rubinstein
This study identifies a steroid-binding site on Complex IV and shows how steroid binding inhibits proton uptake through the K-pathway.
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3 papers
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J. Di Trani, A. Moe, D. Riepl…·J. L. Rubinstein
This study identifies a steroid-binding site on Complex IV and shows how steroid binding inhibits proton uptake through the K-pathway.
J. Di Trani, Z. Liu, L. Whitesell…·J. L. Rubinstein
This study uses cryoEM to analyze the structure and dynamics of the Rieske head domain in Candida albicans Complex III and shows how Inz-5 alters its conformational equilibrium.
A. Moe, J. Di Trani, J. L. Rubinstein, P. Brzezinski
This paper uses cryo-EM and kinetic studies to show that cytochrome c transfers electrons via 2D diffusion along the surface of yeast III2IV1/2 supercomplexes, enhancing electron transfer efficiency.