Author

J. Duffner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

H. J. Kim· 2 shared J. Hixon· 2 shared J. P. Taylor· 2 shared J. Wu· 2 shared K. Wong· 2 shared R. Lemieux· 2 shared R. Meyers· 2 shared B. A. Johnson· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersCell Biology

H. J. Kim

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication

Z. Yang, B. A. Johnson, V. A. Meliopoulos, X. Ju, P. Zhang, M. P. Hughes, J. Wu, K. P. Koreski, T.-C. Chang, G. Wu, J. Hixon, J. Duffner, K. Wong, R. Lemieux, K. G. Lokugamage, , J. P. Taylor

This study identifies the role of G3BP1-N interaction in SARS-CoV-2 replication by showing that disrupting this interaction reduces viral replication and pathogenesis.

bioRxiv · Jun 29, 2023 · PreprintCell Biology

Identification of small molecule inhibitors of G3BP-driven stress granule formation

B. D. Freibaum, J. Messing, H. Nakamura, U. Yurtsever, J. Wu, H. J. Kim, J. Hixon, R. Lemieux, J. Duffner, W. Huynh, K. Wong, M. White, C. Lee, R. Meyers, R. D. Parker, J. P. Taylor

This study identifies two small molecules that inhibit G3BP-driven stress granule formation and dissolve pre-existing granules, showing broad efficacy across cell types and stressors.

bioRxiv · Jun 27, 2023Cell Biology