Author

J. Messing

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biophysics· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

J. P. Taylor· 4 shared B. D. Freibaum· 3 shared H. J. Kim· 2 shared A. Bewick· 1 shared A. E. Harkess· 1 shared A. Singh· 1 shared A. Y. Ting· 1 shared B. C. Meyers· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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4 shared papersCell Biology

J. P. Taylor

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Author profile →

5 papers

Recent·Most cited

Unusual predominance of maintenance DNA methylation in Spirodela polyrhiza

A. E. Harkess, A. Bewick, Z. Lu, P. Fourounjian, J. Messing, T. Michael, R. J. Schmitz, B. C. Meyers

This study shows that Spirodela polyrhiza maintains CG and CHG DNA methylation at repeats without the RdDM pathway or small RNAs, despite losing key methylation genes.

G3: Genes, Genomes, Genetics · Apr 3, 2024Peer-reviewedPlant Biology

Tunable metastability of condensates reconciles their dual roles in amyloid fibril formation

T. Das, F. Zaidi, M. Farag, K. M. Ruff, T. S. Mahendran, A. Singh, X. Gui, J. Messing, J. P. Taylor, P. R. Banerjee, R. V. Pappu, T. Mittag

The paper shows that separable interactions in A1-LCD allow tunable metastability of condensates, which can suppress amyloid fibril formation even with ALS mutations.

bioRxiv · Feb 28, 2024Biophysics

Identification of small molecule inhibitors of G3BP-driven stress granule formation

B. D. Freibaum, J. Messing, H. Nakamura, U. Yurtsever, J. Wu, H. J. Kim, J. Hixon, R. Lemieux, J. Duffner, W. Huynh, K. Wong, M. White, C. Lee, R. Meyers, R. D. Parker, J. P. Taylor

This study identifies two small molecules that inhibit G3BP-driven stress granule formation and dissolve pre-existing granules, showing broad efficacy across cell types and stressors.

bioRxiv · Jun 27, 2023Cell Biology

Dynamic mapping of proteome trafficking within and between living cells by TransitID

W. Qin, J. S. Cheah, C. Xu, J. Messing, B. D. Freibaum, S. Boeynaems, J. P. Taylor, N. D. Udeshi, S. A. Carr, A. Y. Ting

TransitID maps proteome trafficking between cellular compartments and between cells with nanometer resolution, revealing new roles for stress granules and intercellular signaling.

bioRxiv · Feb 7, 2023Cell Biology

High fidelity reconstitution of stress granules and nucleoli in mammalian cellular lysate

B. D. Freibaum, J. Messing, H. J. Kim, J. P. Taylor

This paper introduces a system for high fidelity reconstitution of stress granules and nucleoli in mammalian cellular lysate, bridging in vitro and live cell studies of membraneless organelles.

bioRxiv · Sep 14, 2020Cell Biology