Author

J. Dufloo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 6 Immunology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 8 Research Focus:host-pathogen & immune response· 8 Organism:human· 8 Assay:proteomics· 4 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1

Frequent Co-Authors

O. Schwartz· 5 shared C. Planchais· 4 shared D. Planas· 4 shared F. Guivel-Benhassine· 4 shared H. Mouquet· 4 shared R. Sanjuan· 4 shared T. Bruel· 4 shared F. Porrot· 3 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersMicrobiology

O. Schwartz

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Viral entry is a weak barrier to zoonosis

J. Dufloo, I. Andreu-Moreno, A. Valero-Rello, R. Sanjuan

The paper experimentally tests the ability of viral receptor-binding proteins from 100+ enveloped RNA viruses to enter human cells, finding that most can do so, with variation among families and host factors playing a role.

bioRxiv · Jan 22, 2024Microbiology

Temperature impacts SARS-CoV-2 spike fusogenicity and evolution

J. Dufloo, R. Sanjuan

This study shows that temperature affects SARS-CoV-2 spike fusogenicity and evolution, with higher temperatures increasing fusion and specific mutations showing temperature-dependent effects.

bioRxiv · Dec 20, 2023Microbiology

Cell type-specific adaptation of the SARS-CoV-2 spike

M. Carrascosa-Saez, M.-C. Marques, The IBV-COVID19-Pipeline, R. Geller, S. F. Elena, A. Rahmeh, J. Dufloo, R. Sanjuan

This study shows how SARS-CoV-2 spike protein adapts to different human cell types through mutations that affect entry efficiency and receptor affinity.

bioRxiv · Dec 20, 2023Microbiology

Sex and species associated differences in Complement-mediated immunity in Humans and Rhesus macaques

N. S. Kelkar, B. S. Goldberg, J. Dufloo, T. Bruel, O. Schwartz, A. J. Hessell, M. E. Ackerman

This study compares complement-mediated immunity differences between humans and rhesus macaques, finding sex-based variations in humans and species-specific differences in complement activity.

bioRxiv · Oct 23, 2023Immunology

Resistance of Omicron subvariants BA.2.75.2, BA.4.6 and BQ.1.1 to neutralizing antibodies

D. Planas, T. Bruel, I. Staropoli, F. Guivel-Benhassine, F. Porrot, P. Maes, L. Grzelak, M. Prot, S. Mougari, C. Planchais, J. Puech, M. Saliba, R. Sahraoui, F. Femy, N. Morel, , O. Schwartz

This study evaluates the neutralizing antibody resistance of SARS-CoV-2 Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to monoclonal antibodies and sera from vaccinated individuals.

bioRxiv · Nov 17, 2022Microbiology

Potent Human Broadly SARS-CoV-2 Neutralizing IgA and IgG Antibodies Effective Against Omicron BA.1 and BA.2

C. Planchais, I. Fernandez, T. Bruel, G. Dias de Melo, M. Prot, M. Beretta, P. Guardado-Calvo, J. Dufloo, L. M. Molinos-Albert, M. Backovic, J. Chiaravalli, E. Giraud, B. Vesin, L. Conquet, L. Grzelak, , H. Mouquet

The paper identifies potent broadly neutralizing IgA and IgG antibodies against SARS-CoV-2 variants, including Omicron BA.1 and BA.2, from memory B cells in convalescents.

bioRxiv · Apr 1, 2022Immunology

SARS-CoV-2 Alpha, Beta and Delta variants display enhanced Spike-mediated Syncytia Formation

M. M. Rajah, M. Hubert, E. Bishop, N. Saunders, R. Robinot, L. Grzelak, D. Planas, J. Dufloo, S. Gellenoncourt, A. Bongers, M. Zivaljic, C. Planchais, F. Guivel-Benhassine, F. Porrot, H. Mouquet, , O. Schwartz

This study compares syncytia formation by SARS-CoV-2 Alpha, Beta, and Delta variants to D614G, finding enhanced fusogenicity and differential effects of mutations on ACE2 binding and antibody escape.

bioRxiv · Jun 11, 2021Microbiology

Syncytia formation by SARS-CoV-2 infected cells

J. Buchrieser, J. Dufloo, M. Hubert, B. Monel, D. Planas, M. M. Rajah, C. Planchais, F. Porrot, F. Guivel-Benhassine, S. van der Werf, N. Casartelli, H. Mouquet, T. Bruel, O. Schwartz

This study shows SARS-CoV-2 infected cells form syncytia via Spike protein-mediated fusion, regulated by IFITMs and TMPRSS2.

The EMBO Journal · Nov 4, 2020Peer-reviewedMicrobiology